A necklace of graduated pearls makes a classic statement. The 6mm glass pearls below are a good place to start, and you certainly aren't limited to white.
To illustrate what you can do, see how Susie used 6mm pearls all the way up to 14mm in her Ultimate Classic Necklace. This sets up perfectly for a bold, round focal piece. She used a disco bead (no longer available), but what do you think of this 18mm etched pink composite flower to go with a set of white pearls and add some color?